Middleton/West Madison Medical Instrument Cluster Businesses
contact : Mike Davis : mdavis@city.middleton.wi.us

One of the world's foremost biotechnology companies, Genzyme is dedicated to making a major positive impact on the lives of people with serious diseases. Genzyme is a leader in the effort to develop and apply the most advanced technologies in the life sciences to address a range of unmet medical needs. The company's products and services are focused on rare inherited disorders, kidney disease, orthopedics, transplant and immune disease, cancer, and diagnostic testing. Genzyme's commitment to innovation continues today with a substantial research and development program focused on genetic diseases, immune system disorders, heart disease, and cancer.

PPD is a leading global contract research organization providing discovery, development and post-approval services as well as compound partnering programs. Our clients and partners include pharmaceutical, biotechnology, medical device, academic and government organizations. PPD applies innovative technologies, therapeutic expertise and a commitment to quality to help its clients and partners maximize returns on their R&D investments and accelerate the delivery of safe and effective therapeutics to patients.

The TomoTherapy Hi·Art System® is a new, revolutionary way to treat cancer with radiation. With the TomoTherapy Hi·Art System®, the physician can check the location of the patient's tumor before each treatment, then deliver painless and precise radiation therapy based on a carefully customized plan. TomoTherapy combines precise 3-D imaging from computerized tomography (CT scanning) with highly targeted radiation beams.

GE Healthcare—Lunar. This division of GE Healthcare develops bone densitometers -- X-ray or ultrasound scanning machines that measure bone density as a way of diagnosing osteoporosis and other metabolic bone diseases. The densitometers also aid doctors in fracture risk assessment and in monitoring patients' response to therapy. GE Healthcare Lunar's Prodigy Advance, part of its Axial DEXA (dual energy x-ray absorptiometry) product line, detects subtle bone density changes in the hip and spine, and its Achilles InSight and Achilles Express ultrasound devices measure bone density through the heel. GE Healthcare Lunar markets its products worldwide.

Catalent Pharma Solutions offers a wide variety of development, drug delivery, manufacturing, and packaging services. Catalent’s Middleton, Wisconsin facility offers its proprietary GPEx® technology for the engineering of high expressing and stable mammalian cell lines for the manufacture of recombinant proteins. Catalent’s GPEx® technology routinely produces high expressing, stable and clonal cell lines in serum free media in less than five months after receipt of cDNA. In addition to carrying out GPEx® cell line engineering, Catalent’s Middleton facility carries out process development, analytical development and cGMP manufacturing services utilizing stirred tank, stainless steel bioreactors for products produced from any mammalian cell line. These projects are supported by the viral clearance, assay development fill/finish, and additional capabilities of other Catalent facilities. Catalent is interested in meeting potential clients looking for cell line engineering services, and/or cGMP manufacturing services (including cGMP production from mammalian cell lines produced by other technologies). For more information, contact our business development group at gpexinfo@catalent.com (email) or visit our website at www.gpextech.com or for information about other Catalent facilities visit us at www.catalent.com.

Headquartered in Madison, ORBITEC is Wisconsin’s aerospace research and product development leader, proving strong in the use of the Small Business Innovative Research Program as a catalyst for technology and product development.